Anavar
Oxandrolone · Var
Mild oral oxandrolone; favored in cutting and female use due to low androgenicity.
Overview
Anavar (oxandrolone) is an oral 17-alpha-alkylated DHT derivative, originally reintroduced clinically for weight gain after trauma, burns, and chronic infection. An added oxygen atom at the A-ring gives it a high anabolic-to-androgenic ratio and one of the mildest side-effect profiles in the oral AAS group, which is why research protocols have favored it in cutting contexts and in female use. It binds the androgen receptor and does not aromatize and is not 5-alpha-reduced (already a DHT derivative). Its 9.5-hour half-life supports twice-daily oral dosing. Hepatotoxicity is rated mild relative to other 17-alpha-alkylated orals, though liver enzyme monitoring still applies, and lipids (notably HDL suppression) are the main harm-reduction target. HPTA suppression occurs but is dose- and duration-dependent.
Pharmacokinetic summary
- Model tier
- Advanced (t½ + Cmax + Tmax + F)
- Half-life
- 0.4 days
- Cmax
- 772 ng/dL
- Tmax
- 0.1 days
- Bioavailability
- 63%
- Typical dose
- 10–50 mg
Harm reduction
- Aromatizes
- No
- DHT derivative
- Yes
- Hepatotoxicity
- mild
- Injection frequency
- Oral, 2×/day
Related compounds
Halotestin
Extremely hepatotoxic oral; pure strength/aggression, minimal hypertrophy.
Anadrol
Potent oral mass builder; high water retention and significant hepatotoxicity.
Dianabol
Classic oral mass builder; short half-life, strong aromatization. Simple model — peak calibrated.
Protocols featuring Anavar
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