Dianabol
Methandrostenolone · Dbol · Methandienone
Classic oral mass builder; short half-life, strong aromatization. Simple model — peak calibrated.
Overview
Dianabol (methandrostenolone, methandienone) is the original oral anabolic steroid, a 17-alpha-alkylated testosterone derivative introduced in 1958. The 17-alpha-methyl group resists first-pass hepatic metabolism, making it orally active but hepatotoxic (rated moderate). It binds the androgen receptor and drives rapid nitrogen retention and glycogen storage, which is why it became the classic mass-builder. Its 5.25-hour half-life means serum levels swing hard, so research protocols have split dosing into 2-3 administrations per day. It aromatizes strongly to estradiol, so water retention, gynecomastia, and blood pressure are the central harm-reduction concerns, alongside liver enzyme and lipid monitoring. HPTA suppression is rapid and complete.
Pharmacokinetic summary
- Model tier
- Simple (t½ + F, Tmax estimated)
- Half-life
- 0.2 days
- Cmax
- 63.1 ng/dL
- Bioavailability
- 95%
- Typical dose
- 15–50 mg
Harm reduction
- Aromatizes
- Yes
- DHT derivative
- No
- Hepatotoxicity
- moderate
- Injection frequency
- Oral, 2–3×/day
Related compounds
Halotestin
Extremely hepatotoxic oral; pure strength/aggression, minimal hypertrophy.
Anadrol
Potent oral mass builder; high water retention and significant hepatotoxicity.
Turinabol
Oral cross between Dbol and Clostebol; low water retention, moderate liver toxicity. Peak calibrated.
Protocols featuring Dianabol
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