Anadrol
Oxymetholone · A50 · Drol
Potent oral mass builder; high water retention and significant hepatotoxicity.
Overview
Anadrol (oxymetholone) is a potent oral 17-alpha-alkylated DHT derivative, originally introduced clinically for anemia and osteoporosis and now used for hereditary angioedema. Despite being a DHT derivative it has an unusual quirk: it aromatizes (weakly, via a non-standard pathway), which is why users report significant water retention and estrogenic effects. It binds the androgen receptor and drives erythropoiesis strongly, which is the basis for its mass-building reputation. Its 8-hour half-life supports once- or twice-daily oral dosing. The dominant harm-reduction concerns are hepatotoxicity (rated severe among the orals), dyslipidemia, and blood pressure, so liver enzymes, lipids, and hematocrit are the monitoring priorities. HPTA suppression is rapid and complete.
Pharmacokinetic summary
- Model tier
- Advanced (t½ + Cmax + Tmax + F)
- Half-life
- 0.3 days
- Cmax
- 500 ng/dL
- Tmax
- 0.1 days
- Bioavailability
- 95%
- Typical dose
- 25–100 mg
Harm reduction
- Aromatizes
- Yes
- DHT derivative
- Yes
- Hepatotoxicity
- severe
- Injection frequency
- Oral, 1–2×/day
Related compounds
Halotestin
Extremely hepatotoxic oral; pure strength/aggression, minimal hypertrophy.
Dianabol
Classic oral mass builder; short half-life, strong aromatization. Simple model — peak calibrated.
Turinabol
Oral cross between Dbol and Clostebol; low water retention, moderate liver toxicity. Peak calibrated.
Protocols featuring Anadrol
Comments
Loading comments…