Nandrolone Decanoate
Deca · Nandrolone Deca
Long-acting 19-nor (Deca-Durabolin); collagen/joint benefits, very long clearance.
Overview
Nandrolone decanoate (Deca-Durabolin) is the decanoate ester of 19-nortestosterone, a 19-nor androgen originally introduced clinically for osteoporosis, cachexia, and anemia. Free nandrolone binds the androgen receptor and is notable for weak aromatization (roughly 20% of testosterone's rate, preferentially to estrone) and for 5-alpha-reduction to the less androgenic dihydronandrolone, which is why its androgenic side-effect profile is comparatively mild. Its 10.2-day half-life produces a peak near 1.8 days and a long tail that reaches steady state over many weeks. Research protocols have used 1-2 injections per week. The main harm-reduction concern is not liver stress (rated none) but the exceptionally long detection window: the 19-norandrosterone metabolite is detectable for 4-9 months in controlled dosing studies. HPTA suppression is profound and recovery is slow.
Pharmacokinetic summary
- Model tier
- Advanced (t½ + Cmax + Tmax + F)
- Half-life
- 10 days
- Cmax
- 800 ng/dL
- Tmax
- 1.8 days
- Bioavailability
- 73%
- Typical dose
- 100–400 mg
Harm reduction
- Aromatizes
- Yes
- DHT derivative
- No
- Injection frequency
- 1–2×/week
Related compounds
Nandrolone Phenylpropionate
Short-acting 19-nor (NPP); faster clearance than Deca. Good for frontloading.
Testosterone Enanthate
Long-acting testosterone ester; the most common TRT and cycle base. Reaches steady state in ~5 weeks.
Testosterone Cypionate
Standard US TRT ester with a slightly longer release tail than enanthate. Steady state ~4–5 weeks.
Protocols featuring Nandrolone Decanoate
Comments
Loading comments…