Feminizing HRT: Estradiol Valerate + Progesterone
Representative feminizing HRT with injectable estradiol valerate and oral progesterone.
Concentration over time
| Date | Progesterone (Oral) | Estradiol Valerate |
|---|---|---|
| W1 | 0.00 | 0.00 |
| W2 | 0.00 | |
| W3 | 0.00 | |
| W5 | 0.00 | |
| W6 | 240.77 | |
| W7 | 212.48 | |
| W9 | 166.58 | |
| W10 | 271.07 | |
| W11 | 212.49 | |
| W13 | 166.58 | |
| W14 | 271.07 | |
| W15 | 212.49 | |
| W17 | 166.58 |
Protocol summary
Feminizing HRT: Estradiol Valerate + Progesterone · 16 weeks starting Jul 20, 26
- Estradiol Valerate — 5.00 mg Every 7 days, weeks 0–16
- Progesterone (Oral) — 100.0 mg Every day, weeks 5–16
Protocol overview
- Category
- trt hrt
- Duration
- 16 weeks
- Compounds
- 2
- Tags
- hrt, estradiol, progesterone, female
Compounds in this protocol
- Estradiol Valerate — 5 mg, every-7-days
- Progesterone (Oral) — 100 mg, every-day (weeks 5-16)
How to read this protocol
The chart above shows the modeled blood concentration of each compound over the 16-week duration. Each compound accumulates toward steady state (roughly 5 half-lives). The peak-to-trough ratio within each dose interval depends on the injection frequency relative to the half-life.
Use the [peak-trough estimator](/tools/peak-trough) to see predicted levels at any point, or the [clearance calculator](/tools/clearance) to estimate washout after the protocol ends. The [PCT planner](/pct-planner) estimates when to start post-cycle therapy.
Educational only. Not medical advice. Concentration values are modeled estimates based on population pharmacokinetics, not predictions of individual blood levels.