Peptides Weight LossMetabolic
Semaglutide Oral (Rybelsus)
Rybelsus · Oral Sema
Oral semaglutide with very low bioavailability; taken fasting.
🚧 Expanded guide coming soon. This compound has PK data and a source — a full overview, mechanism, and dosing guide is pending editorial review.
Pharmacokinetic summary
- Model tier
- Advanced (t½ + Cmax + Tmax + F)
- Half-life
- 0.5 days
- Cmax
- 232.38 nmol/L
- Tmax
- 0.1 days
- Bioavailability
- 1%
- Typical dose
- 3–14 mg
Related compounds
Semaglutide Injection (Ozempic/Wegovy)
Long-acting GLP-1 receptor agonist for type 2 diabetes and weight loss; weekly injection.
Dulaglutide (Trulicity)
Long-acting GLP-1 agonist for type 2 diabetes and weight loss; weekly subcutaneous injection.
Tirzepatide (Mounjaro)
Dual GIP/GLP-1 agonist for weight loss and diabetes; weekly injection, strong efficacy.
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