PCT Fundamentals

Post-cycle therapy (PCT) aims to restore endogenous testosterone production after the hypothalamic-pituitary-gonadal (HPG) axis has been suppressed by exogenous hormones.

When to start

PCT must begin only after suppressive compounds have sufficiently cleared. Starting too early is futile — circulating exogenous hormone continues to suppress the axis. Use clearance timing (≈5 × half-life) as a guide; our PCT Planner estimates this from your specific compounds.

The SERM backbone

• Nolvadex (Tamoxifen) (tamoxifen) — blocks estrogen receptors at the hypothalamus and pituitary, boosting LH/FSH.
• Clomid (Clomiphene) (clomiphene) — similar mechanism; often paired with Nolvadex.

HCG

HCG mimics LH and is used during or just before PCT to resensitize / restore testicular volume before SERMs drive endogenous production.

What PCT cannot do

PCT cannot instantly restore the HPG axis. Full recovery takes weeks to months and varies by individual, cycle length, and compounds used.