# Trenbolone Acetate

*Also known as: Tren A, Fina*

Short-acting 19-nor ester requiring every-other-day dosing. Simple model — peak calibrated.

## Overview

Trenbolone acetate is the short-acting acetate ester of trenbolone, the potent 19-nor androgen originally formulated as Finaplix for cattle. It binds the androgen receptor at roughly three times testosterone's affinity, drives nitrogen retention and protein synthesis aggressively, and does not aromatize or undergo 5-alpha-reduction. Its 1.5-day half-life (36 hours) is the defining feature: serum levels swing fast, so research protocols have used every-other-day or daily injection to hold levels flat. The short ester also means faster clearance if side effects appear. Harm-reduction priorities mirror the enanthate version (blood pressure, lipids, kidney markers, psychological effects) plus a distinct acute injection cough reported post-injection. Hepatotoxicity is rated mild and HPTA suppression is severe and rapid.

## Pharmacokinetics

- **Model tier:** simple
- **Half-life:** 1.5 days (36 hours)
- **Cmax:** 68.9 ng/dL
- **Bioavailability:** 87%

## Dosing

- **Default dose:** 50 mg
- **Typical range:** 35–100 mg
- **Units:** ng/dL

## Harm reduction

- **Aromatizes:** No
- **DHT derivative:** No
- **Hepatotoxicity:** mild
- **Injection frequency:** EOD–daily
- **Interaction notes:** Trenbolone + PDE5 inhibitors (e.g. tadalafil) raises risk of cardiovascular strain.

## Detection time (anti-doping)

- **Window:** 20–35 days post-last-dose
- **Target metabolite:** Epitrenbolone (17α-trenbolone) glucuronide
- **Assay:** LC-MS/MS
- **Notes:** Short-acting ester; epitrenbolone glucuronide detectable up to ~32 days (Sobolevsky & Rodchenkov 2015). Controlled-study detection ceiling ~1 month.

## Source

- **Label:** Trenbolone ester PK
- **URL:** https://www.sciencedirect.com/science/article/abs/pii/S002228602030452X
- **Notes:** Cmax calibrated to ng/dL serum peak.

---

**Canonical URL:** https://anabolicdex.com/compounds/trenbolone-acetate
**Plot:** https://anabolicdex.com/plot?compound=trenbolone-acetate
