# Testosterone Gel (Testogel/AndroGel)

*Also known as: Testogel, AndroGel, Transdermal T*

Transdermal testosterone gel providing steady low-level delivery. Transfer risk to others.

## Overview

Testosterone gel (AndroGel, Testogel) is a transdermal preparation used for testosterone replacement therapy, providing steady low-level delivery without the peaks and troughs of injectable esters. The alcohol-based gel carries testosterone across the skin into the systemic circulation, building a subcutaneous reservoir that releases slowly over the day and produces a stable serum profile. The compound has an apparent terminal half-life of roughly 72 hours reflecting the skin reservoir, reaches peak serum in roughly 10 hours, and has about 10% bioavailability because most of the applied dose remains on the skin surface. Effects include stable eugonadal testosterone with less hematocrit and estradiol swing than injectable forms, while the dominant concern is secondary transfer to partners or children via skin contact. Harm reduction centers on covering the application site, washing hands thoroughly, keeping the area covered until dry, and timing application to avoid close skin contact with others.

## Pharmacokinetics

- **Model tier:** advanced
- **Half-life:** 3.0 days (71.599999992 hours)
- **Cmax:** 600 ng/dL
- **Tmax:** 0.4 days
- **Bioavailability:** 10%

## Dosing

- **Default dose:** 50 mg
- **Typical range:** 25–100 mg
- **Units:** ng/dL

## Harm reduction

- **Aromatizes:** Yes
- **DHT derivative:** No
- **Injection frequency:** Daily topical

## Source

- **Label:** Wang et al. 2004 (AndroGel PK)
- **URL:** https://pubmed.ncbi.nlm.nih.gov/24732865/
- **Notes:** Cmax calibrated to ng/dL serum peak (transdermal, steady delivery). Transdermal bioavailability ~10%.

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**Canonical URL:** https://anabolicdex.com/compounds/testosterone-gel
**Plot:** https://anabolicdex.com/plot?compound=testosterone-gel