# Superdrol

*Also known as: Methasterone*

Design steroid methasterone; notorious for severe hepatotoxicity. Simple model — peak calibrated.

## Overview

Superdrol (methasterone) is a synthetic oral anabolic steroid first marketed in 2005 as an over-the-counter prohormone before being classified as a controlled substance. It is a 17-alpha-alkylated DHT derivative with two methyl groups that resist hepatic breakdown and boost oral bioavailability. Methasterone binds the androgen receptor with high affinity, producing rapid strength and mass gains. The dataset records a half-life of about 10 hours, Cmax near 120 ng/dL, and bioavailability around 50% at the default 20 mg dose. Documented community protocols split dosing twice daily because of that short half-life. The defining harm-reduction concern is severe hepatotoxicity, with case reports of cholestatic jaundice and acute liver injury plus notable lipid and cardiovascular disruption.

## Pharmacokinetics

- **Model tier:** simple
- **Half-life:** 0.4 days (10.0000008 hours)
- **Cmax:** 119.8 ng/dL
- **Bioavailability:** 50%

## Dosing

- **Default dose:** 20 mg
- **Typical range:** 10–30 mg
- **Units:** ng/dL

## Harm reduction

- **Aromatizes:** No
- **DHT derivative:** Yes
- **Hepatotoxicity:** severe
- **Injection frequency:** Oral, 2×/day

## Detection time (anti-doping)

- **Window:** 7–11 days post-last-dose
- **Target metabolite:** M2 (2α,17α-dimethyl-5α-androstane-3α,17β-diol)
- **Assay:** LC-QTOF-MS
- **Notes:** Long-term metabolite M2 detectable up to ~11 days.

## Source

- **Label:** Wikipedia (Methasterone)
- **URL:** https://en.wikipedia.org/wiki/Methasterone
- **Notes:** Cmax calibrated to ng/dL serum peak.

---

**Canonical URL:** https://anabolicdex.com/compounds/superdrol
**Plot:** https://anabolicdex.com/plot?compound=superdrol