# Nandrolone Decanoate

*Also known as: Deca, Nandrolone Deca*

Long-acting 19-nor (Deca-Durabolin); collagen/joint benefits, very long clearance.

## Overview

Nandrolone decanoate (Deca-Durabolin) is the decanoate ester of 19-nortestosterone, a 19-nor androgen originally introduced clinically for osteoporosis, cachexia, and anemia. Free nandrolone binds the androgen receptor and is notable for weak aromatization (roughly 20% of testosterone's rate, preferentially to estrone) and for 5-alpha-reduction to the less androgenic dihydronandrolone, which is why its androgenic side-effect profile is comparatively mild. Its 10.2-day half-life produces a peak near 1.8 days and a long tail that reaches steady state over many weeks. Research protocols have used 1-2 injections per week. The main harm-reduction concern is not liver stress (rated none) but the exceptionally long detection window: the 19-norandrosterone metabolite is detectable for 4-9 months in controlled dosing studies. HPTA suppression is profound and recovery is slow.

## Pharmacokinetics

- **Model tier:** advanced
- **Half-life:** 10.2 days (244.79999999999998 hours)
- **Cmax:** 800 ng/dL
- **Tmax:** 1.8 days
- **Bioavailability:** 73%

## Dosing

- **Default dose:** 200 mg
- **Typical range:** 100–400 mg
- **Units:** ng/dL

## Harm reduction

- **Aromatizes:** Yes
- **DHT derivative:** No
- **Injection frequency:** 1–2×/week

## Detection time (anti-doping)

- **Window:** 120–270 days post-last-dose
- **Target metabolite:** 19-norandrosterone (19-NA)
- **Assay:** GC-MS/MS + GC/C/IRMS
- **Notes:** Controlled single-dose study: 19-NA detectable in 6/11 subjects at 4 months, 3/11 at 9 months (Palonek 2016). Multi-dose regimens may extend further.

## Source

- **Label:** JCEM nandrolone decanoate
- **URL:** https://academic.oup.com/jcem/article/90/5/2624/2836761

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**Canonical URL:** https://anabolicdex.com/compounds/nandrolone-decanoate
**Plot:** https://anabolicdex.com/plot?compound=nandrolone-decanoate