# Human Growth Hormone (HGH)

*Also known as: HGH, Somatropin, GH*

Recombinant growth hormone; supports lipolysis, recovery, IGF-1 elevation.

## Overview

Human growth hormone, or somatropin, is a recombinant form of the pituitary peptide hormone used for growth-hormone deficiency and off-label for recovery, lipolysis, and anti-aging contexts. It acts through hepatic and peripheral IGF-1 generation and direct lipolytic effects, driving nitrogen retention, fat mobilization, and connective tissue repair. The compound has a short roughly 4-hour serum half-life, peaks within a few hours of subcutaneous injection, and shows roughly 63% bioavailability, though its downstream effects through IGF-1 persist far longer, so daily dosing sustains the anabolic and lipolytic signal. Common effects include improved body composition and recovery, while known risks at supraphysiological doses are fluid retention, carpal tunnel symptoms, insulin resistance, and elevated IGF-1 linked to long-term concerns. Harm reduction centers on confirming genuine growth-hormone deficiency or clear clinical indication before use, on regular IGF-1, fasting glucose, and thyroid monitoring, and on sourcing recombinant product given widespread counterfeiting.

## Pharmacokinetics

- **Model tier:** advanced
- **Half-life:** 0.2 days (4.1333333327999995 hours)
- **Cmax:** 622.9 ng/mL
- **Tmax:** 0.2 days
- **Bioavailability:** 63%

## Dosing

- **Default dose:** 1 mg
- **Typical range:** 0.5–4 mg
- **Units:** ng/mL

## Source

- **Label:** Nature / PMC HGH PK
- **URL:** https://www.nature.com/articles/pr198896
- **Notes:** 1 mg ≈ 3 IU.

**Tags:** muscle-building, recovery-healing, anti-aging-longevity

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**Canonical URL:** https://anabolicdex.com/compounds/hgh
**Plot:** https://anabolicdex.com/plot?compound=hgh