# GHRP-6

*Also known as: GHRP6*

Ghrelin-receptor secretagogue that increases GH and notably stimulates appetite.

## Overview

GHRP-6 is a first-generation growth hormone secretagogue that acts on the ghrelin (GHS-R1a) receptor to amplify growth hormone pulses from the pituitary. Unlike GHRH analogs, it works through a separate pathway, which is why stacking the two classes produces a stronger GH response than either alone. Its defining feature beyond GH release is appetite stimulation, a direct consequence of ghrelin-receptor activation, which makes it the appetite-heavy member of the GHRP family. The estimated half-life is roughly one hour with around 50% subcutaneous bioavailability, so research contexts typically reference multiple daily doses. Human pharmacokinetic data is limited and GHRP-6 is not an approved medication.

## Pharmacokinetics

- **Model tier:** simple
- **Half-life:** 0.0 days (0.96 hours)
- **Bioavailability:** 50%

## Dosing

- **Default dose:** 0.15 mg
- **Typical range:** 0.1–0.3 mg
- **Units:** ng/mL

## Source

- **Label:** Estimated
- **Notes:** Ghrelin-mimetic secretagogue; notable appetite stimulation.

**Tags:** muscle-building, anti-aging-longevity

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**Canonical URL:** https://anabolicdex.com/compounds/ghrp-6
**Plot:** https://anabolicdex.com/plot?compound=ghrp-6